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? HIV ??????????????????????????? ...???????????Progressive Multifocal. Leukoencephalopathy: PML?????????. 2020???. ???????????PML???. CQ1-1 PML ??????????? ?????®????300mg ??????????????????progressive multifocal leukoence- phalopathy; PML?? JC ?????JC virus; JCV??????. ?????????????? ... ???????????PML????1 ????? ??? 29-??? ...???????????progressive multifocal leukoencepha- lopathy; PML?? JC ?????JC virus; JCV???????. ????????????????????? ... ?????,??????,??????????????????? ...???????????progressive multifocal leukoencepha- lo pathy; PML???????????????JC ?????JC virus; JCV????????????????? ... ??????????????????? ???????????? 2018 ? 11 ??? 2019 ? 10 ????????? PML ??????????????. ??????????????MS?????????????? PML ?? ... ???????????PML????1 ????????????????progressive multifocal leukoen- cephalopathy; PML???JCV?John Cunningham virus???. ????????????????????????? ... ?????????? ???????? 2023PML ? JCV ???????????????????????????????????????. ????????????????????????????? 1?2??? ... ?????????? ???????? 2017???????????progressive multifocal leukoencephalopathy: PML??????????. ????????????????????????????human ... ????????? ?? - ?????????????????... ??????. ????? (1)??21?? (? )? ??????????????????????? 1????. ?????????? (1). (2). (3). ? ? - ???????WROJapan2023?????????. ????? ... ??????. ???????????????????????????????? ??40????? - ???????????????????????????????????????????????. ??????????????????????????????????????. ? ... ???? rs??I??????????????10?13????. ??????????????????????. ??????????????????????. ??? ...
